Dual-energy CT of liver metastases in patients with uveal melanoma

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Dual-energy CT of liver metastases in patients with uveal melanoma

OBJECTIVE To investigate the value of different kVp images of dual-energy CT (DECT) for the detection of liver metastases. METHODS 20 Patients with uveal melanoma were investigated with DECT of the liver. In each patient contrast-enhanced DECT imaging with arterial delay was performed. Number and size of metastases were documented on arterial phase 80-kVp images, virtual 120-kVp images and fo...

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Combined treatment of uveal melanoma liver metastases

Uveal melanoma (UM) is the most prevalent intraocular malignant tumor in the Western world. The prognosis of survival in the presence of metastatic disease is 2-7 months, depending on the treatment applied. - This article presents a case of metastatic UM with successful complex treatment of liver metastases. - A 49-year old female, underwent removal of the right eyeball in 1996 due to a histolo...

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Molecular characteristics of liver metastases from uveal melanoma.

PURPOSE The liver is the most common site of systemic metastases from uveal melanoma (UM). Such metastases usually continue to develop despite the application of current treatment modalities. This study was conducted to obtain insight into the molecular pathways that underlie the development of UM metastasis and thus to identify potential novel therapeutic pathways for this disease. METHODS M...

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Molecular pathways mediating liver metastasis in patients with uveal melanoma.

Uveal melanoma arises from melanocytes located in the uveal tract of the eye and is the most common primary intraocular tumor in adults. Metastatic liver disease is the overwhelming cause of death in uveal melanoma patients, with almost 50% of patients developing liver metastases up to 15 years after diagnosis. Most of these patients do not present with any evidence of overt metastasis at the t...

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ژورنال

عنوان ژورنال: European Journal of Radiology Open

سال: 2016

ISSN: 2352-0477

DOI: 10.1016/j.ejro.2016.10.003